IMMUNOLOGICAL STUDIES OF AORTITIS SYNDROME (1) COMPLEMENT FIXATION TEST AND PRECIPITATION TEST

[Immunological studies of aortitis syndrome. (1) Complement fixation test and precipitation test].

概要 補体結 合反 応,沈 降反応を用いて大動脈炎症候群におけ る抗大動脈抗体の検出 を試みた .補体 結合反応 では,疾 患別には,陽 性率が本症候群で23例 中17例(73.9%)と もつ とも高 く,抗 体価 も本症 候群 では,1:20以 上 が23例 中12例(52.1%)と 高い例が多かつた .本症 候群での抗体 価は,初 回検 査 時の成績 のみ を とる と,自 覚症 状(閉 塞症状)の 程度 との間に若干の相関が得 られ,一 方,各 症例の経 時的変 化をみる と,抗 体価の変動は 自覚症状,発 熱,検 査所見,ス テ ロ イ ド治 療の有無 と,か な りの 相関 を示 した .また抗大動脈抗体は抗末梢動脈抗体 ・抗心抗 体 ・抗腎抗 体とは異なつた ものであ ると 考 え られ た.さ らに,抗 原 として ヒ ト・イ ヌいずれ の大動脈を用いて も同様の成績が...

Detection of rotavirus by Latex Agglutination Test (Rotales); Comparison with Electron Microscopy and Complement Fixation Test

Further immunological studies of aortitis syndrome.

An elevated titer of anti-aorta antibodies was detected with a significantly higher frequency in cases of aortitis syndrome than in those of other diseases by the complement fixation test and tannic acid hemagglutination test. This finding indicates participation of immune mechanism in the development of aortitis syndrome. The direct fluorescent antibody technique disclosed that aorta antigens ...

Quantitative micro-complement fixation test.

A quantitative micro-complement fixation test capable of detecting nanogram quantities of antigen is described. The test is simple to perform and is highly reproducible. Typical results from three antigen-antibody systems are given.

Studies on a complement fixation test for Herpes simplex.

Although the neutralization test is, in general, satisfactory for immunologic studies with a diversity of viruses, it is cumbersome and expensive. The complement fixation test, in contrast, is simple and rapid and has been successfully applied to a number of viral diseases, especially for diagnostic purposes. In the case of herpes simplex virus infections, however, the literature concerning the...